Q&A Genmab 2019-11-08

	8/11 17:53 af Solsen	Mr Winkel You have pointed out CD20/CD3 and DR5/DR5 as partnering candidates. Are they still in that category and what timeline can we expect.
	8/11 17:55 af Jan Van de Winkel	These are certainly programs that could potentially target very large markets, for which Genmab would ideally have a military style partner for expansive clinical development. We anticipate that this will be further clarified in 2020.
	8/11 17:55 af Bulder	Do you know if Novartis has plans of resuming what GSK started a few years ago, studies of sc ofatumumab in RA?
	8/11 17:56 af Jan Van de Winkel	Novartis is highly excited by the potential of SubCu Ofatumumab in MS.
	8/11 17:56 af Solsen	Mr Winkel Could you give om some more info regarding the liver toxicity in the DR5/DR5 trial. Could it possibly be crucial for this hexabody ?
	8/11 17:57 af Jan Van de Winkel	It is too early to further comment on the signals we have observed. The protocol for evaluation of HexaBody DR5/DR5 has been amended and we are currently actively enrolling patients in the study and expect to present data in 2020.
	8/11 17:57 af Solsen	Mr Winkel Is it still you belive that you can attract big pharma/powerhouses if you want to keep the US marked 100% Or are you looking for other partners than top 10 Pharma ?
	8/11 17:59 af Jan Van de Winkel	We are currently interacting with various potential candidates for partnerships, all of which are open to Genmab keeping significant US commercial rights, which is one of our key goals for our next therapeutic candidates.
	8/11 17:59 af kkjoel	Mr. Winkel, David referred in your cc. to US IMS-salesfigures for October at $39 mio. pr. week. Are these reel, net salesnumbers, rebates included?
	8/11 18:00 af Jan Van de Winkel	The IMS numbers are gross numbers before rebates or discounts.
	8/11 18:00 af Solsen	Mr Winkel How do you se price increase on Revlimid impact on first line sales for dara. And what effect will patent expire in 2023/24 for Revlimid have.
	8/11 18:01 af Jan Van de Winkel	We see an increasing number of patients in frontline getting daratumumab as part of their treatment regimens and expect that number to go up further with availability of new data independent of the pricing of Revlimid.
	8/11 18:02 af Bulder	Anything serious behind the enrollment hold of the Auriga study?
	8/11 18:02 af Jan Van de Winkel	No, this is a technical hold because of the fact that Janssen needs to further validate the tests to assess MRD negativity.
	8/11 18:03 af Solsen	Mr Winkel In the Biontech collaboration is there any agreement om how you share potential markeds - US vs ROW - marketing and sales ?
	8/11 18:04 af Jan Van de Winkel	The exact details of the collaboration are not public, but what can be stated that Genmab will have a dominant role in commercialization.
	8/11 18:04 af Legolas23	Thank you for spending time with us today, Mr. Jan Winkel. It means a lot to us at PI. In connection with Q3, you say that you will promise 2 partner deals. Can we expect 50/50 deal?
	8/11 18:05 af Jan Van de Winkel	We have been very explicit about the need to have a partner for one or two products and keep at least 50% of the ownership rights.
	8/11 18:06 af Legolas23	Can you comment on whether the tests with BMS (checkmate) are still active. Is there progress and can we expect new before the turn of the year?
	8/11 18:07 af Jan Van de Winkel	To our knowledge, Daratumumab has been evaluated in combination with Opdivo in studies with multiple arms which are still on CT.gov.
	8/11 18:07 af Solsen	Mr Winkel. The DuoBody-CD3x5T4 in new to us. From which collaboration ? And when are you planning IND ? Have you any further info ?
	8/11 18:08 af Jan Van de Winkel	This is a 100% Genmab program which created high excitement in preclinical studies. Further information will follow in the coming time.
	8/11 18:09 af Helge Larsen/PI-redaktør	Great. We have 2 questions more left for you.
	8/11 18:09 af Relax	In a previous Q&A it was expressed that Genmab is considering having their own product on the market in 2025. Can it please be explained why it is necessary to build a sales organization already 5 years ahead of a having a product ready.

	8/11 18:10 af Jan Van de Winkel	The wish to have a product on the market by 2025 is linked to our 2025 vision...
	8/11 18:10 af Jan Van de Winkel	This does not mean that we have to wait until 2025.
	8/11 18:10 af kkjoel	Mr. Winkel, the number of shares traded every day i US is negligible. Are you sure it "pays back" in the long run?
	8/11 18:12 af Jan Van de Winkel	It is still early days and the markets are very wobbly. What we see is a steeply increased interest in Genmab, as reflected by a much higher interest in meetings with management and increased visbility in the world's largest innovation eco-system.
	8/11 18:12 af Helge Larsen/PI-redaktør	This was all we had for you this time. Thank you for joining us and for the many fulfilling answers to the broad range of qualified questions from our investors here at ProInvestor.com. We look very much forward to having you back again here in the near future for a Q&A after Q4.
	8/11 18:13 af Jan Van de Winkel	Thank you all for very inspiration and thoughtful questions. I look forward to touch bases again after Q4 and wish you all a relaxing and good weekend for now.
	8/11 18:14 af Helge Larsen/PI-redaktør	This session has ended.